Medical devices have transformed human healthcare during the past half century, from the development of rapid diagnostic devices to medical implants to restore physiological functions to bioinstruments that sustain life following severe trauma. Our faculty are engaged in multi-disciplinary research to improve these devices even further by studying synthetic and natural biomaterials that can prevent thrombosis and infection, accelerate wound healing, or support cell growth in tissue engineered devices. Ongoing exploration of new materials and devices at the interface of engineering, physical, chemical and health sciences provide the enabling building blocks for realization of systems with transformational capabilities necessary to meet societal needs.